By Dr. Franjo Grotenhermen
Dear Rick Simpson,
You are in all probability probably the most well-known character when it comes to the medical use of hashish by most cancers sufferers. Many determined people, affected by most cancers and different critical maladies, put their belief in you and place nice hope in your recommendation.
You are conscious of this duty once you write in your e-book, Rick Simpson Oil – Nature’s Answer for Cancer, “I think anyone including myself, if put in a position of public trust, should expect to have their activities while working for the public watched very closely,” (Pos. 2528, Kindle). It is my conclusion, nevertheless, that you haven’t taken the right measures commensurate with such nice duty. I hope that sooner or later, you are able to do higher.
I share your view once you write, “As I have stated many times, it is our watch and is our sacred responsibility to see that mankind will survive and prosper. Doctors will begin to follow the Hippocratic Oath and governments will begin to work for the greater good of the people. This is the only path we can follow which makes any sense and, if ignored, the destruction of the human race can be the only result,” (Pos. 2517, Kindle). And you proceed, “My mission is simply to provide the truth to everyone possible, so together we can effect change,” (Pos. 3460, Kindle).
But I’ve to state that you’re not taking many necessary details into consideration – a lot to the detriment of individuals. You admit that you’re “not a doctor” and don’t “have the qualifications necessary to become one,” (pos. 1485, Kindle), however you’re taking the freedom of exaggerating guarantees of therapeutic that don’t get up to factual examination.
I would like to make clear what one may interpret as overly harsh criticism, nevertheless, is inevitable, by six examples:
Lack of Knowledge
You write, “Decarboxylation occurs when the molecules within the oil have been rotated to the delta 9 position with the use of heat so they become more and medicinally active,” (Pos. 717, Kindle).
It is a reality, nevertheless, prior to decarboxylation, the substance is already delta-9-THC. With regard to the corresponding double bond within the THC molecule, nothing modifications by way of the method. Decarboxylation means removing of carbon dioxide. This response converts the naturally current THC acid (THCA) within the plant into phenolic THC that’s liable for a lot of the therapeutic results of delta-9-THC. I learn in your web site that you simply encourage to embrace plant-based meals within the food regimen, claiming that the proteins contained in crops possess cancer-fighting properties, as properly. However, it isn’t proteins, however the phytochemicals, reminiscent of flavonoids, which can possess such properties.
You write, “I think it’s of benefit to the patient for the oil to be administered as close as possible to a tumor or whatever is being treated. Therefore, if you have bowel problems, suppositories would likely work best, but if you have something like throat or stomach cancer, etc. I would ingest the oil by mouth,” (Pos. 1012, Kindle).
The fact is, that additionally in instances of stomach carcinomas, cannabinoids attain the most cancers by means of the physique’s circulatory system. One ought to know some primary drugs, in order to not depend on beliefs, as a result of they could end up to be mistaken ones.
Confusing Amount and Concentration
You write, “By volume, it would be impossible for a hemp tincture to be as potent as pure oil. A patient could ingest their doses mixed with alcohol, but what good would taking this medication with alcohol do the patient?” (Pos. 1043, Kindle).
The fact is, that a diluted hashish oil with a 5 % THC content material, ingested orally, has the equivalent pharmaceutical impact as a hashish extract or hashish oil with a THC content material of 50 %. This is as a result of the impact just isn’t based mostly on focus; it’s based mostly on absolutely the quantity. One milliliter of 50 % hashish extract incorporates the identical quantity of THCmillilitersilitres of a 5 % extract, which is strictly 500 milligrams of THC. Only when utilized externally does focus play a task.
You write that, “On average, there is about one person in ten who will freely tell the world what had healed them but the majority of patients tend to remain more or less quiet … Since most people will not come forward, it makes my tasks that much harder and many will continue to die because those who have used these extracts refuse to discuss what they have witnessed,” (Pos. 1192, Kindle). And additional, “Since 2003, I have provided these extracts to roughly 5000 people who were suffering with all types of medical problems. Many of these patients had several medical issues which needed attention but most were brought under control or cured with the use of this oil,” (Pos. 1377, Kindle).
You write your self that solely about one in ten sufferers handled by you gives suggestions on the success of the remedy, and also you complain that you don’t hear again from most of them. Despite this, you undauntedly declare that each one most cancers sufferers, even these you by no means heard again from, have been healed by using hashish oil. Claims based mostly on such restricted knowledge turn into utterly absurd when contrasted with the truth that, relying on classification, there are between 100 and 1,000 kinds of most cancers.
You write that, “I always recommend high-grade oils for internal use in the treatment of serious conditions. A high-grade extract should contain THC levels in the range of 80-90% and produce an extremely sedative, yet euphoric effect when ingested. The higher the quality of the oil, the more pronounced will be its healing effects,” (Pos. 368, Kindle).
The fact is that apart from THC, different cannabinoids possess cancer-inhibiting properties – particularly, CBD (cannabidiol). There are indications that in some forms of tumors, CBD might play a extra necessary position than THC. Moreover, there are robust indications that a mixture of THC and CBD is simpler than THC alone, with regard to at the least sure kinds of most cancers. Among different elements, this may be of nice significance when THC is insufficiently tolerated, and better dosages are out of the query. In such instances, a remedy with excessive dosages of CBD might be tried. You developed your principle 15 years in the past when CBD was not but in focus. However, our information of the effectiveness of entire hashish and cannabinoids within the remedy of most cancers are of preliminary nature. And we should all the time take new knowledge into consideration, providing our sufferers probably the most up to date recommendation and coverings attainable.
Warning Against Effective Therapies
You write, “Unfortunately, many people who come to me have been badly damaged by the medical system with their chemo and radiation, etc. The damage such treatments cause have a lasting effect in people who have suffered these so-called treatments are the hardest to cure. But don’t despair, for even if you have been badly damaged, this oil still has a 70 to 80% success rate,” (Pos. 970, Kindle).
Now I arrive at a really critical concern. You advocate that each one most cancers sufferers keep away from commonplace remedies as a result of radiation remedy and chemotherapy each trigger injury. Instead, all sufferers might be healed together with your hashish oil. We don’t know the precise success price of your hashish oil, and you may’t probably realize it both since you’ve had too little suggestions out of your shoppers. But we do know the success charges of ordinary therapies. In Germany, of the 500,000 people recognized with most cancers annually, 280,000 are healed. This comes out to round 55%. As lately as 1980, two-thirds of all most cancers sufferers succumbed to their ailment.
If the restoration price from normal remedies continues to rise, and the speed of restoration for these handled with hashish stays unknown, what number of sufferers have died needlessly, following your recommendation?
And what number of sufferers, who might have been healed, if that they had acquired a mixture of cannabinoids and traditional therapies, might have survived had they not solely relied on hashish?
That you current issues wrongly by not understanding chemistry, physiology, and drugs isn’t what I maintain towards you. One doesn’t essentially want to perceive all the small print. However, this can be a query of life and demise, and such a critical problem, that you’ve to be accused of not dwelling up to your duty and subsequently your personal aspirations.
This is concerning the wellbeing of people who flip to us. They have a proper to the absolute best and most up-to-date info, as properly the absolute best recommendation. When it comes to medical remedy, particularly when confronted with critical sickness, it isn’t sufficient to deal with sufferers by counting on good intentions and vehemently presenting a conviction.
I’m satisfied that your popularity amongst supporters would enhance in the event you have been in a position to revise and replace your recommendation. I’m satisfied that hashish and cannabinoid therapies are of worth within the remedy of most cancers. Let us handle their potential with nice care and consciousness!
From the e-book: “Grotenhermen F. Cannabis gegen Krebs: Der Stand der Wissenschaft und praktische Folgerungen für die Therapie” [Cannabis against Cancer: The State of Science and Practical Conclusions for the Treatment]. Solothurn, Switzerland: Nachtschatten Verlag, 2017. With a preface by Dr Burkhard Hinz, Director of the Institute for Pharmacology and Toxicology, University of Rostock, Germany.
Franjo Grotenhermen, M.D., born in 1957, studied drugs on the University of Cologne. He runs a medical follow, primarily devoted to the medical use of hashish and cannabinoids. Dr. Grotenhermen is the founder and chairman of the German Association for Cannabis as Medicine (ACM), founder and government director of the International Association for Cannabinoid Medicines (IACM) (www.cannabis-med.org) and chairman of the Medical Cannabis Declaration (MCD). He is editor of the IACM-Bulletin, which is revealed bi-weekly in a number of languages and editor of the web journal CANNABINOIDS, revealed on the web site of the IACM. He is a principal of the nova-Institute based mostly close to Cologne and writer of many articles, books, and guide chapters on the therapeutic potential, pharmacology, and toxicology of cannabinoids.
Photo courtesy of Allie Beckett